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(R)-SKBG-1

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Catalog No. T79156Cas No. 2955634-67-8

(R)-SKBG-1 is an inhibitor of the RNA-binding protein NONO, with an EC50 value of 1.5 μM in 22Rv1 cells. (R)-SKBG-1 reduces mRNA and protein expression of the androgen receptor (AR) and its splice variants (AR-FL and AR-V7), inhibits the proliferation of various cancer cells, and affects the transcriptome and proteome of cancer cells.

(R)-SKBG-1
Other Forms of (R)-SKBG-1:
(S)-SKBG-1T895282955618-24-1
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(R)-SKBG-1

😃Good
Catalog No. T79156Cas No. 2955634-67-8
(R)-SKBG-1 is an inhibitor of the RNA-binding protein NONO, with an EC50 value of 1.5 μM in 22Rv1 cells. (R)-SKBG-1 reduces mRNA and protein expression of the androgen receptor (AR) and its splice variants (AR-FL and AR-V7), inhibits the proliferation of various cancer cells, and affects the transcriptome and proteome of cancer cells.
Pack SizePriceAvailabilityQuantity
1 mg$72Backorder
5 mg$153Backorder
10 mg$282Backorder
25 mg$622Backorder
1 mL x 10 mM (in DMSO)$167Backorder
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Product Introduction

Bioactivity
Description
(R)-SKBG-1 is an inhibitor of the RNA-binding protein NONO, with an EC50 value of 1.5 μM in 22Rv1 cells. (R)-SKBG-1 reduces mRNA and protein expression of the androgen receptor (AR) and its splice variants (AR-FL and AR-V7), inhibits the proliferation of various cancer cells, and affects the transcriptome and proteome of cancer cells.
Chemical Properties
Molecular Weight495.98
FormulaC22H26ClN3O6S
Cas No.2955634-67-8
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (161.3 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0162 mL10.0811 mL20.1621 mL100.8105 mL
5 mM0.4032 mL2.0162 mL4.0324 mL20.1621 mL
10 mM0.2016 mL1.0081 mL2.0162 mL10.0811 mL
20 mM0.1008 mL0.5041 mL1.0081 mL5.0405 mL
50 mM0.0403 mL0.2016 mL0.4032 mL2.0162 mL
100 mM0.0202 mL0.1008 mL0.2016 mL1.0081 mL

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Keywords

AndrogenReceptorAndrogen Receptor
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