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3-Methylbut-2-enoic acid

Name: 3-Methylbut-2-enoic acid
Brand: TargetMol
SKU: T5305
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5305Cas No. 541-47-9

Alias Senecioic acid, 3-Methylcrotonic Acid, 3,3-Dimethylacrylic Acid

3-Methylbut-2-enoic acid (Senecioic acid) appears in the urine of patients with 3-Methylcrotonic aciduria, which is a disorder characterized by urine that contains increased amounts of 3-methylcrotonic acid.

3-Methylbut-2-enoic acid

🥰Excellent

Purity: 99.86%

Catalog No. T5305Alias Senecioic acid, 3-Methylcrotonic Acid, 3,3-Dimethylacrylic AcidCas No. 541-47-9

Pack Size	Price	Availability	Quantity
1 g	$29	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.86%

Resource Download

COA GC LCMS HNMR

Product Introduction

Bioactivity

Description	3-Methylbut-2-enoic acid (Senecioic acid) appears in the urine of patients with 3-Methylcrotonic aciduria, which is a disorder characterized by urine that contains increased amounts of 3-methylcrotonic acid.
Synonyms	Senecioic acid, 3-Methylcrotonic Acid, 3,3-Dimethylacrylic Acid

Chemical Properties

Molecular Weight	100.12
Formula	C₅H₈O₂
Cas No.	541-47-9
Smiles	C\C(C)=C\C(O)=O
Relative Density.	3.45.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (499.4 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (19.98 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	9.9880 mL	49.9401 mL	99.8801 mL	499.4007 mL
5 mM	1.9976 mL	9.9880 mL	19.9760 mL	99.8801 mL
10 mM	0.9988 mL	4.9940 mL	9.9880 mL	49.9401 mL
20 mM	0.4994 mL	2.4970 mL	4.9940 mL	24.9700 mL
50 mM	0.1998 mL	0.9988 mL	1.9976 mL	9.9880 mL
100 mM	0.0999 mL	0.4994 mL	0.9988 mL	4.9940 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc