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Cassiaside B2

Name: Cassiaside B2
Brand: TargetMol
SKU: TN1470
Price: 276 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1470Cas No. 218155-40-9

Cassiaside B2 is an inhibitor of protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A).Cassiaside B2 is an agonist of the 5-HT2C receptor with anti-allergic activity.Cassiaside B2 is one of the active ingredients in the naphthylpyrone reference extract (NRE).

Cassiaside B2

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Purity: 99.97%

Catalog No. TN1470Cas No. 218155-40-9

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$276	-	In Stock
5 mg	$639	-	In Stock
10 mg	$956	-	In Stock
25 mg	$1,420	-	In Stock
50 mg	$1,920	-	In Stock
100 mg	$2,590	Backorder	Backorder

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.97%

Resource Download

COA HPLC

Product Introduction

Bioactivity

Description	Cassiaside B2 is an inhibitor of protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A).Cassiaside B2 is an agonist of the 5-HT2C receptor with anti-allergic activity.Cassiaside B2 is one of the active ingredients in the naphthylpyrone reference extract (NRE).
Targets&IC50	MAO-A:40.57 µM

Chemical Properties

Molecular Weight	920.82
Formula	C₃₉H₅₂O₂₅
Cas No.	218155-40-9
Smiles	O(C=1C2=C(C=C3C(=C2O)C(=O)C=C(C)O3)C=C(OC)C1)[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@@H](O[C@@H]6O[C@H](CO[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@H](O)[C@H](O)[C@H]6O)[C@H](O)[C@@H](CO)O5)[C@@H](O)[C@H](O)[C@H]4O
Relative Density.	1.77 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (54.30 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.0860 mL	5.4299 mL	10.8599 mL	54.2994 mL
5 mM	0.2172 mL	1.0860 mL	2.1720 mL	10.8599 mL
10 mM	0.1086 mL	0.5430 mL	1.0860 mL	5.4299 mL
20 mM	0.0543 mL	0.2715 mL	0.5430 mL	2.7150 mL
50 mM	0.0217 mL	0.1086 mL	0.2172 mL	1.0860 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc