Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML-309 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). It reversibly and selective inhibits IDH1R132H over wild-type IDH1 (IC50s = 96 and 36,500 nM, respectively). ML-309 reduces 2-hydroxyglutarate production in U87 MG glioblastoma cells (EC50 = 55 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 98.00 | |
5 mg | 35 days | $ 265.00 | |
10 mg | 35 days | $ 473.00 |
Description | ML-309 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). It reversibly and selective inhibits IDH1R132H over wild-type IDH1 (IC50s = 96 and 36,500 nM, respectively). ML-309 reduces 2-hydroxyglutarate production in U87 MG glioblastoma cells (EC50 = 55 nM). |
Molecular Weight | 521.03 |
Formula | C29H30ClFN4O2 |
CAS No. | 1355327-02-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
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ML-309 (hydrochloride) 1355327-02-4 ML309 (hydrochloride) ML309 ML 309 (hydrochloride) ML 309 ML-309 inhibitor inhibit