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Anti-SLAMF7 Antibody (8I592)
(Synonyms: SLAMF7, Novel Ly9, FOAP-12, CS1, CRACC, CD319, CD2 subset 1, 19A) Copy Product Info
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Synonyms: SLAMF7, Novel Ly9, FOAP-12, CS1, CRACC, CD319, CD2 subset 1, 19A
Catalog No. TMAH-01096 Copy Product Info
🥰Excellent
Anti-SLAMF7 Antibody (8I592) is an antibody targeting SLAMF7. Anti-SLAMF7 Antibody (8I592) can be used in ELISA,FCM,IHC.
Anti-SLAMF7 Antibody
(8I592)
(8I592)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-SLAMF7 Antibody (8I592) is an antibody targeting SLAMF7. Anti-SLAMF7 Antibody (8I592) can be used in ELISA,FCM,IHC. |
| Synonyms | SLAMF7, Novel Ly9, FOAP-12, CS1, CRACC, CD319, CD2 subset 1, 19A |
| Ig Type | Mouse IgG2a |
| Clone | 8I592 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC:1:20-1:200; FCM:1:20-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. Expressed |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B. Downstream signaling implicates PLCG1, PLCG2 and PI3K. In addition to heterotypic NK cells-target cells interactions also homotypic interactions between NK cells may contribute to activation. However, in the absence of SH2D1B, inhibits NK cell function. Acts also inhibitory in T-cells. May play a role in lymphocyte adhesion. In LPS-activated monocytes negatively regulates production of proinflammatory cytokines. Isoform 3 does not mediate any NK cell activation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human SLAMF7 Protein |
| Antigen Species | Human |
| Gene Name | SLAMF7 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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