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Antitumor agent-38

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Catalog No. T61616Cas No. 2744193-34-6

Antitumor agent-38 is a highly effective antitumor compound that exhibits antiproliferative activity towards cancer cells. It induces cell cycle arrest specifically at the late S and G2/M phase, while not impeding microtubule formation or altering cell morphology [1].

Antitumor agent-38

Antitumor agent-38

😃Good
Catalog No. T61616Cas No. 2744193-34-6
Antitumor agent-38 is a highly effective antitumor compound that exhibits antiproliferative activity towards cancer cells. It induces cell cycle arrest specifically at the late S and G2/M phase, while not impeding microtubule formation or altering cell morphology [1].
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$2,1408-10 weeks8-10 weeks
50 mg$2,7858-10 weeks8-10 weeks
100 mg$3,5208-10 weeks8-10 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Antitumor agent-38 is a highly effective antitumor compound that exhibits antiproliferative activity towards cancer cells. It induces cell cycle arrest specifically at the late S and G2/M phase, while not impeding microtubule formation or altering cell morphology [1].
In vitro
Antitumor agent-38 (compound 9h) demonstrates antiproliferative effects with GI50 values of 0.66, 0.85, 0.76, 4.12, and 3.67 μM against A549, MDA-MB-231, KB, KB-VIN, and MCF-7 cells, respectively [1]. Furthermore, this compound (0.58, 1.74 μM; 24 h) significantly induces cell cycle arrest at the late S and G2/M phases in MDA-MB-231 cells, confirmed by Cell Cycle Analysis at 0.85 and 1.74 μM over 24 hours [1].
Chemical Properties
Molecular Weight380.44
FormulaC22H24N2O4
Cas No.2744193-34-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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