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AMD-070 hydrochloride

Name: AMD-070 hydrochloride
Brand: TargetMol
SKU: T22565
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T22565Cas No. 880549-30-4

AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.

AMD-070 hydrochloride

🥰Excellent

Purity: 98.57%

Catalog No. T22565Cas No. 880549-30-4

AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.

Pack Size	Price	Availability
1 mg	$35	In Stock
5 mg	$80	In Stock
10 mg	$132	In Stock
25 mg	$238	In Stock
50 mg	$386	In Stock
100 mg	$619	In Stock
1 mL x 10 mM (in DMSO)	$88	In Stock

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Batch Information

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Purity:98.57%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.
Targets&IC50	HIV-1 (NL4.3 strain):9 nM (In PBMCs), HIV-1 (NL4.3 strain):3 nM (IC90, in MT-4 cells), HIV-1 (NL4.3 strain):26 nM (IC90, in PBMCs), HIV-1 (NL4.3 strain):1 nM (In MT-4 cells), 125 I-CXCL12-CXCR4:13 nM

Chemical Properties

Molecular Weight	385.93
Formula	C₂₁H₂₈ClN₅
Cas No.	880549-30-4
Smiles	C1C[C@@H](C2=C(C1)C=CC=N2)N(CCCCN)CC3=NC4=CC=CC=C4N3.Cl
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (155.47 mM), Sonication is recommended.

H2O: 50 mg/mL (129.56 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5911 mL	12.9557 mL	25.9114 mL	129.5572 mL
5 mM	0.5182 mL	2.5911 mL	5.1823 mL	25.9114 mL
10 mM	0.2591 mL	1.2956 mL	2.5911 mL	12.9557 mL
20 mM	0.1296 mL	0.6478 mL	1.2956 mL	6.4779 mL
50 mM	0.0518 mL	0.2591 mL	0.5182 mL	2.5911 mL
100 mM	0.0259 mL	0.1296 mL	0.2591 mL	1.2956 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc