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TIM-3-IN-1

Name: TIM-3-IN-1
Brand: TargetMol
SKU: T63029
Rating: 4.5 (1 reviews)

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TIM-3-IN-1 is a useful tool to enable further studies on the biology of TIM-3 immunoregulation in cancer. TIM-3-IN-1 is used in immuno-oncology research systems to investigate TIM-3–mediated immune checkpoint regulation, T cell exhaustion mechanisms, and tumor immune microenvironment modulation in cancer immunology models.

TIM-3-IN-1

Cas No. 2883237-04-3

Pack Size	Price	USA Stock	Global Stock
25 mg	$1,520	10-14 weeks	10-14 weeks
50 mg	$1,980	10-14 weeks	10-14 weeks
100 mg	$2,500	10-14 weeks	10-14 weeks

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	469.90
Formula	C₂₀H₁₆ClN₇O₃S
Cas No.	2883237-04-3
Smiles	O=C1NC=2C=C(Cl)C(=CC2C3=NC(=NN13)C)C=4C=CC(=CC4C)NS(=O)(=O)C5=NC=CN5
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (170.25 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1281 mL	10.6406 mL	21.2811 mL	106.4056 mL
5 mM	0.4256 mL	2.1281 mL	4.2562 mL	21.2811 mL
10 mM	0.2128 mL	1.0641 mL	2.1281 mL	10.6406 mL
20 mM	0.1064 mL	0.5320 mL	1.0641 mL	5.3203 mL
50 mM	0.0426 mL	0.2128 mL	0.4256 mL	2.1281 mL
100 mM	0.0213 mL	0.1064 mL	0.2128 mL	1.0641 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Related Tags: TIM-3-IN-1 formula | TIM-3-IN-1 molecular weight

TIM-3-IN-1

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In Vivo Formulation Calculator (Clear solution)

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