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Methyl Dehydroabietate

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Catalog No. T67200Cas No. 1235-74-1
Alias (1R,4aS,10aR)-methyl 7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylate

Methyl Dehydroabietate is a natural diterpenoid that induces the expression of proliferator-activated receptor alpha (PPARα) in liver and PPARγ in adipose tissue in mice, reduces obesity-induced glucose and insulin tolerance, and possesses a variety of biological activities such as antimicrobial, anti-inflammatory, and antioxidant.

Methyl Dehydroabietate

Methyl Dehydroabietate

😃Good
Purity: 99.55%
Catalog No. T67200Alias (1R,4aS,10aR)-methyl 7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylateCas No. 1235-74-1
Methyl Dehydroabietate is a natural diterpenoid that induces the expression of proliferator-activated receptor alpha (PPARα) in liver and PPARγ in adipose tissue in mice, reduces obesity-induced glucose and insulin tolerance, and possesses a variety of biological activities such as antimicrobial, anti-inflammatory, and antioxidant.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$30In StockIn Stock
50 mg$42In StockIn Stock
100 mg$59-In Stock
200 mg$86-In Stock
1 mL x 10 mM (in DMSO)$46-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.55%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
Methyl Dehydroabietate is a natural diterpenoid that induces the expression of proliferator-activated receptor alpha (PPARα) in liver and PPARγ in adipose tissue in mice, reduces obesity-induced glucose and insulin tolerance, and possesses a variety of biological activities such as antimicrobial, anti-inflammatory, and antioxidant.
Synonyms(1R,4aS,10aR)-methyl 7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylate
Chemical Properties
Molecular Weight314.46
FormulaC21H30O2
Cas No.1235-74-1
SmilesC[C@@]12[C@]([C@@](C(OC)=O)(C)CCC1)(CCC=3C2=CC=C(C(C)C)C3)[H]
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 40 mg/mL (127.2 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+90% Corn Oil: 2 mg/mL (6.36 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1801 mL15.9003 mL31.8005 mL159.0027 mL
5 mM0.6360 mL3.1801 mL6.3601 mL31.8005 mL
10 mM0.3180 mL1.5900 mL3.1801 mL15.9003 mL
20 mM0.1590 mL0.7950 mL1.5900 mL7.9501 mL
50 mM0.0636 mL0.3180 mL0.6360 mL3.1801 mL
100 mM0.0318 mL0.1590 mL0.3180 mL1.5900 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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