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FC131 TFA (606968-52-9 free base)

🥰Excellent
Catalog No. TP1348Cas No. 842166-42-1
Alias FC131 TFA

FC131 TFA (606968-52-9 free base) (FC131 TFA) is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv activity.

FC131 TFA (606968-52-9 free base)
Other Forms of FC131 TFA (606968-52-9 free base):

FC131 TFA (606968-52-9 free base)

🥰Excellent
Purity: 99.67%
Catalog No. TP1348Alias FC131 TFACas No. 842166-42-1
FC131 TFA (606968-52-9 free base) (FC131 TFA) is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv activity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$48In StockIn Stock
5 mg$123In StockIn Stock
10 mg$197In StockIn Stock
25 mg$332In StockIn Stock
50 mg$496In StockIn Stock
100 mg$693In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.67%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
FC131 TFA (606968-52-9 free base) (FC131 TFA) is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv activity.
Targets&IC50
[125I]-SDF1-CXCR4:4.5 Nm
SynonymsFC131 TFA
Chemical Properties
Molecular Weight843.85
FormulaC38H48F3N11O8
Cas No.842166-42-1
SmilesFC(F)(F)C(=O)O.N=C(N)NCCC[C@@H]4NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](Cc2cc3ccccc3cc2)NC4=O)CCCNC(=N)N
Relative Density.no data available
ColorWhite
AppearanceSolid
Sequence{2-Naph-Ala}-{Gly}-{Tyr}-{Arg}-{Arg}
Sequence Short2-Naph-AGYRR
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 250 mg/mL (296.26 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (5.93 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.1850 mL5.9252 mL11.8504 mL59.2522 mL
5 mM0.2370 mL1.1850 mL2.3701 mL11.8504 mL
10 mM0.1185 mL0.5925 mL1.1850 mL5.9252 mL
20 mM0.0593 mL0.2963 mL0.5925 mL2.9626 mL
50 mM0.0237 mL0.1185 mL0.2370 mL1.1850 mL
100 mM0.0119 mL0.0593 mL0.1185 mL0.5925 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

HIVProteaseHIV ProteaseHIVFC-131 TFA (606968-52-9 free base)FC131 TFA (606968529 free base)FC131 TFA (606968 52 9 free base)CXCR4606968-52-9 free base606968-52-9
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