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Anti-FGF1 Antibody (6Y815)
(Synonyms: HBGF-1, HBGF1, GLIO703, fibroblast growth factor 1 (acidic), FGF-α, FGF-alpha, FGFA, FGF-1, ECGF-β, ECGF-beta, ECGFB, ECGFA, ECGF, AFGF) Copy Product Info
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Synonyms: HBGF-1, HBGF1, GLIO703, fibroblast growth factor 1 (acidic), FGF-α, FGF-alpha, FGFA, FGF-1, ECGF-β, ECGF-beta, ECGFB, ECGFA, ECGF, AFGF
Catalog No. TMAH-00428 Copy Product Info
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Anti-FGF1 Antibody (6Y815) is an antibody targeting FGF1. Anti-FGF1 Antibody (6Y815) can be used in ELISA,FCM,IF.
Anti-FGF1 Antibody
(6Y815)
(6Y815)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-FGF1 Antibody (6Y815) is an antibody targeting FGF1. Anti-FGF1 Antibody (6Y815) can be used in ELISA,FCM,IF. |
| Synonyms | HBGF-1, HBGF1, GLIO703, fibroblast growth factor 1 (acidic), FGF-α, FGF-alpha, FGFA, FGF-1, ECGF-β, ECGF-beta, ECGFB, ECGFA, ECGF, AFGF |
| Ig Type | mIgG2a |
| Clone | 6Y815 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF:1:50-1:200; FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Secreted. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytosol. Nucleus. |
| Tissue Specificity | Predominantly expressed in kidney and brain. Detected at much lower levels in heart and skeletal muscle. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3. Its binding to integrin, subsequent ternary complex formation with integrin and FGFR1, and the recruitment of PTPN11 to the complex are essential for FGF1 signaling. Induces the phosphorylation and activation of FGFR1, FRS2, MAPK3/ERK1, MAPK1/ERK2 and AKT1. Can induce angiogenesis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human FGF1 Protein |
| Antigen Species | Human |
| Gene Name | FGF1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Neuroscience, Cancer, Cardiovascular, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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