Shopping Cart

Your shopping cart is currently empty

Araloside A

Name: Araloside A
Brand: TargetMol
SKU: T4S0290
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T4S0290Cas No. 7518-22-1

Alias Chikusetsusaponin IV

Araloside A (Chikusetsusaponin IV) might relieve cutaneous symptoms caused by excessive apoptotic cell death in the skin through the Fas/FasL pathway.

Araloside A

Copy Product Info

😃Good

Purity: 99.88%

Catalog No. T4S0290Alias Chikusetsusaponin IVCas No. 7518-22-1

Araloside A (Chikusetsusaponin IV) might relieve cutaneous symptoms caused by excessive apoptotic cell death in the skin through the Fas/FasL pathway.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$31	In Stock	In Stock
5 mg	$73	In Stock	In Stock
10 mg	$106	In Stock	In Stock
25 mg	$176	In Stock	In Stock
50 mg	$262	In Stock	In Stock
100 mg	$389	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$118	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.88%

Color:White

Resource Download

COA

Product Introduction

Araloside A AI Summary

Araloside A inhibits fMLP/CB-stimulated superoxide anion generation in human neutrophils by 14.6% at 30 µM compared to the control. It also reduces fMLP/CB-activated human neutrophil degranulation, specifically the release of elastase, by 27.6% at 30 µM after 5 minutes, using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as a substrate relative to control. Additionally, Araloside A demonstrates inhibitory activity against hyaluronidase with IC50 values ranging from 24,000 nM to 190,000 nM under different assay conditions. The compound shows a higher potency in inhibiting CaCl2-activated hyaluronidase compared to the unactivated form, with a ratio IC50 of 2.5..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Araloside A (Chikusetsusaponin IV) might relieve cutaneous symptoms caused by excessive apoptotic cell death in the skin through the Fas/FasL pathway.
Targets&IC50	Renin:77.4 μM (IC50)
Synonyms	Chikusetsusaponin IV

Chemical Properties

Molecular Weight	927.08
Formula	C₄₇H₇₄O₁₈
Cas No.	7518-22-1
Smiles	[H][C@@]1(O[C@H]2[C@H](O)[C@@H](O)[C@]([H])(O[C@H]3CC[C@@]4(C)[C@@]([H])(CC[C@]5(C)[C@]4([H])CC=C4[C@]6([H])CC(C)(C)CC[C@@]6(CC[C@@]54C)C(=O)O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C3(C)C)O[C@@H]2C(O)=O)O[C@@H](CO)[C@H](O)[C@H]1O
Relative Density.	1.42 g/cm3 (Predicted)

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25 mg/mL (26.97 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (1.08 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.0787 mL	5.3933 mL	10.7866 mL	53.9328 mL
5 mM	0.2157 mL	1.0787 mL	2.1573 mL	10.7866 mL
10 mM	0.1079 mL	0.5393 mL	1.0787 mL	5.3933 mL
20 mM	0.0539 mL	0.2697 mL	0.5393 mL	2.6966 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc