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STING agonist-18

Name: STING agonist-18
Brand: TargetMol
SKU: T81084
Price: 326 USD
Availability: InStock
Rating: 5 (10 reviews)

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STING agonist-18 is a STING agonist that can be used as a functional module for constructing antibody–drug conjugates (ADCs), for example by conjugation with Trastuzumab, and is applied in studies of cancer immunotherapy.

Cas No. 2138299-68-8

Pack Size	Price	USA Stock	Global Stock
1 mg	$326	-	In Stock
5 mg	$778	-	In Stock
10 mg	$1,230	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	779.85
Formula	C₃₈H₄₅N₁₃O₆
Cas No.	2138299-68-8
Smiles	C(/C=C/CN1C=2C(N=C1NC(=O)C=3N(CC)N=C(C)C3)=CC(C(N)=O)=CC2OC)N4C=5C(N=C4NC(=O)C=6N(CC)N=C(C)C6)=CC(C(N)=O)=CC5OCCCN

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (128.23 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2823 mL	6.4115 mL	12.8230 mL	64.1149 mL
5 mM	0.2565 mL	1.2823 mL	2.5646 mL	12.8230 mL
10 mM	0.1282 mL	0.6411 mL	1.2823 mL	6.4115 mL
20 mM	0.0641 mL	0.3206 mL	0.6411 mL	3.2057 mL
50 mM	0.0256 mL	0.1282 mL	0.2565 mL	1.2823 mL
100 mM	0.0128 mL	0.0641 mL	0.1282 mL	0.6411 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Related Tags: STING agonist-18 chemical structure | STING agonist-18 formula | STING agonist-18 molecular weight