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Anti-TNFR1/CD120a/TNFRSF1A Antibody (7L401) is a Mouse antibody targeting TNFR1/CD120a/TNFRSF1A. Anti-TNFR1/CD120a/TNFRSF1A Antibody (7L401) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $199 | 7-10 days |
Description | Anti-TNFR1/CD120a/TNFRSF1A Antibody (7L401) is a Mouse antibody targeting TNFR1/CD120a/TNFRSF1A. Anti-TNFR1/CD120a/TNFRSF1A Antibody (7L401) can be used in ELISA. |
Alias | tumor necrosis factor receptor superfamily member 1A, TNF-R-I, TNFR60, TNF-R55, TNFR55, TNFR1-d2, TNFR1, TNF-R, TNFAR, TBP1, p60, p55-R, p55, MS5, FPF, CD120a |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 7L401 |
Reactivity | Rat |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat TNFR1/TNFRSF1A/CD120a (rR TNFR1/TNFRSF1A/CD120a; TMPY-03538; NP_037223.1; Met1-Ala211). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-κB, mediate apoptosis, and regulate inflammation processes. |
Conjucates | Unconjugated |
Immunogen | Recombinant Rat TNFR1/TNFRSF1A/CD120a Protein (TMPY-03538) |
Antigen Species | Rat |
Biology Area | Neuroinflammation |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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