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RO5203648 HCl

Name: RO5203648 HCl
Brand: TargetMol
SKU: T34374
Price: 74 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T34374Cas No. 1043491-54-8

Alias RO-5203648, RO5203648, RO 5203648

RO5203648 HCl is a partial agonist of trace amine-related receptor 1 (TAAR1) with antipsychotic and antidepressant-like activities. RO5203648 HCl can be used in studies about neuropsychiatric therapeutics.

RO5203648 HCl

🥰Excellent

Purity: 98.16%

Catalog No. T34374Alias RO-5203648, RO5203648, RO 5203648Cas No. 1043491-54-8

Pack Size	Price	Availability
1 mg	$74	In Stock
5 mg	$178	In Stock
10 mg	$313	In Stock
25 mg	$533	In Stock
50 mg	$768	In Stock
100 mg	$1,080	In Stock
1 mL x 10 mM (in DMSO)	$167	In Stock

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Batch Information

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Purity:98.16%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	RO5203648 HCl is a partial agonist of trace amine-related receptor 1 (TAAR1) with antipsychotic and antidepressant-like activities. RO5203648 HCl can be used in studies about neuropsychiatric therapeutics.
Synonyms	RO-5203648, RO5203648, RO 5203648

Chemical Properties

Molecular Weight	231.08
Formula	C₉H₈Cl₂N₂O
Cas No.	1043491-54-8
Smiles	ClC=1C=C(C=CC1Cl)[C@@H]2N=C(N)OC2
Relative Density.	1.57 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 4.4 mg/mL (19.04 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.3275 mL	21.6375 mL	43.2751 mL	216.3753 mL
5 mM	0.8655 mL	4.3275 mL	8.6550 mL	43.2751 mL
10 mM	0.4328 mL	2.1638 mL	4.3275 mL	21.6375 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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