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Khellin

🥰Excellent
Catalog No. T1431Cas No. 82-02-0
Alias Visammin, Methafrone, Amicardine

Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.

Khellin

Khellin

🥰Excellent
Purity: 99.95%
Catalog No. T1431Alias Visammin, Methafrone, AmicardineCas No. 82-02-0
Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$31In StockIn Stock
25 mg$47In StockIn Stock
50 mg$68In StockIn Stock
100 mg$89In StockIn Stock
500 mg$219In StockIn Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.95%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.
Targets&IC50
EGFR:0.15 µM (IC50)
SynonymsVisammin, Methafrone, Amicardine
Chemical Properties
Molecular Weight260.24
FormulaC14H12O5
Cas No.82-02-0
SmilesCOc1c2ccoc2c(OC)c2oc(C)cc(=O)c12
Relative Density.1.301 g/cm3
Storage & Solubility Information
StorageIn solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 12 mg/mL (46.11 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.8426 mL19.2130 mL38.4261 mL192.1303 mL
5 mM0.7685 mL3.8426 mL7.6852 mL38.4261 mL
10 mM0.3843 mL1.9213 mL3.8426 mL19.2130 mL
20 mM0.1921 mL0.9607 mL1.9213 mL9.6065 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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