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Montelukast

🥰Excellent
Catalog No. T1677Cas No. 158966-92-8
Alias Singular

Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury.

Montelukast
Other Forms of Montelukast:

Montelukast

🥰Excellent
Purity: 99.74%
Catalog No. T1677Alias SingularCas No. 158966-92-8
Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$29In StockIn Stock
50 mgPreferentialIn StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.74%
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Product Introduction

Bioactivity
Description
Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury.
SynonymsSingular
Chemical Properties
Molecular Weight586.18
FormulaC35H36ClNO3S
Cas No.158966-92-8
SmilesCC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1
Relative Density.1.272 g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 1.7 mM, Sonication is recommended.
DMSO: 250 mg/mL (426.49 mM), The compound is unstable in solution. Please use soon.
In Vivo Formulation
10% DMSO+90% Corn Oil: 5 mg/mL (8.53 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM1.7060 mL8.5298 mL17.0596 mL85.2980 mL
DMSO
1mg5mg10mg50mg
5 mM0.3412 mL1.7060 mL3.4119 mL17.0596 mL
10 mM0.1706 mL0.8530 mL1.7060 mL8.5298 mL
20 mM0.0853 mL0.4265 mL0.8530 mL4.2649 mL
50 mM0.0341 mL0.1706 mL0.3412 mL1.7060 mL
100 mM0.0171 mL0.0853 mL0.1706 mL0.8530 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

MontelukastMK-0476MK0476MK 0476liverLeukotrieneReceptorLeukotriene Receptorleukotrieneischemia–reperfusionintestinalinjuryInhibitorinhibiticardiacdamagecysteinylCysLTR1Cysltr1COVID-19asthmaantioxidantALOX5
Related Tags: buy Montelukast | purchase Montelukast | Montelukast cost | order Montelukast | Montelukast chemical structure | Montelukast formula | Montelukast molecular weight
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