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Anti-MEN1 Antibody (5E903)

😃Good
Catalog No. TMAH-00744
Alias SCG2, Menin, MEN 1

Anti-MEN1 Antibody (5E903) is an antibody targeting MEN1. Anti-MEN1 Antibody (5E903) can be used in ELISA, WB.

Anti-MEN1 Antibody (5E903)

Anti-MEN1 Antibody (5E903)

😃Good
Catalog No. TMAH-00744Alias SCG2, Menin, MEN 1
Anti-MEN1 Antibody (5E903) is an antibody targeting MEN1. Anti-MEN1 Antibody (5E903) can be used in ELISA, WB.
Pack SizePriceAvailabilityQuantity
50 μL$208 7-10 days
100 μL$347 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Rabbit Monoclonal

Application: ELISA, WB

Reactivity: Human
AliasSCG2, Menin, MEN 1
Ig Type
Rabbit IgG
Clone
5E903
Reactivity
Human
Verified Activity
Western Blot
-Positive WB detected in: PC-3 whole cell lysate, MCF-7 whole cell lysate, 293 whole cell lysate
-All lanes: MEN1 antibody at 1:2000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 69, 68, 64 kDa
-Observed band size: 75 kDa
Application
ELISA, WB
Recommended Dose
WB:1:500-1:5000.
Antibody Type
Monoclonal
Subcellular LocalizationNucleus. Note=Concentrated in nuclear body-like structures. Relocates to the nuclear matrix upon gamma irradiation.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundEssential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression. May be involved in DNA repair.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human Menin
Antigen Species
Human
Gene ID
4221
Uniprot ID
Biology Area
Epigenetics and Nuclear Signaling, Cancer
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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