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Anti-MEN1 Antibody (5E903) is an antibody targeting MEN1. Anti-MEN1 Antibody (5E903) can be used in ELISA, WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $208 | 7-10 days | |
100 μL | $347 | 7-10 days |
Description | Antibody Type: Recombinant Rabbit Monoclonal Application: ELISA, WB Reactivity: Human |
Alias | SCG2, Menin, MEN 1 |
Ig Type | Rabbit IgG |
Clone | 5E903 |
Reactivity | Human |
Verified Activity | Western Blot -Positive WB detected in: PC-3 whole cell lysate, MCF-7 whole cell lysate, 293 whole cell lysate -All lanes: MEN1 antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 69, 68, 64 kDa -Observed band size: 75 kDa |
Application | ELISA, WB |
Recommended Dose | WB:1:500-1:5000. |
Antibody Type | Monoclonal |
Subcellular Localization | Nucleus. Note=Concentrated in nuclear body-like structures. Relocates to the nuclear matrix upon gamma irradiation. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression. May be involved in DNA repair. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide: Human Menin |
Antigen Species | Human |
Gene ID | 4221 |
Uniprot ID | |
Biology Area | Epigenetics and Nuclear Signaling, Cancer |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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