Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. [1] coumarin-Suberoylanilide hydroxamic acid (c-SAHA) is a SAHA derivative where the anilino cap" group is replaced by 7-amino-4-methylcoumarin to produce a fluorescent probe that competitively binds HDAC. [2] The fluorescence excitation and emission maxima of free c-SAHA is 325 and 400 nm
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 88.00 | |
10 mg | 35 days | $ 333.00 | |
25 mg | 35 days | $ 623.00 |
Description | Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. [1] coumarin-Suberoylanilide hydroxamic acid (c-SAHA) is a SAHA derivative where the anilino cap" group is replaced by 7-amino-4-methylcoumarin to produce a fluorescent probe that competitively binds HDAC. [2] The fluorescence excitation and emission maxima of free c-SAHA is 325 and 400 nm |
Synonyms | coumarin-Suberoylanilide Hydroxamic Acid, coumarin-SAHA |
Molecular Weight | 346.383 |
Formula | C18H22N2O5 |
CAS No. | 1260635-77-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5 mg/mL
DMF: 5 mg/mL
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coumarin-SAHA 1260635-77-5 coumarin SAHA coumarinSAHA coumarin-Suberoylanilide Hydroxamic Acid inhibitor inhibit