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5,6-Benzoflavone

Name: 5,6-Benzoflavone
Brand: TargetMol
SKU: TN6694
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. TN6694Cas No. 6051-87-2

Alias β-Naphthoflavone, beta-NF

5,6-Benzoflavone (β-Naphthoflavone) is an exogenous ligand for the aryl hydrocarbon receptor, which disrupts zinc homeostasis in human hepatocellular carcinoma HepG2 cells. 5,6-Benzoflavone (β-Naphthoflavone) possesses anti-inflammatory and antioxidant activities, inhibits LPS-induced inflammation through the AKT/Nrf-2/HO-1-NF-kappaB signaling axis, inhibits TNF-α-induced ICAM-1 and VCAM-1 expression, which can be used to study neurodegenerative diseases.

5,6-Benzoflavone

🥰Excellent

Purity: 99.88%

Catalog No. TN6694Alias β-Naphthoflavone, beta-NFCas No. 6051-87-2

Pack Size	Price	Availability
100 mg	$30	In Stock
500 mg	$66	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock

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Batch Information

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Purity:99.88%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description

Synonyms

β-Naphthoflavone, beta-NF

Chemical Properties

Molecular Weight	272.3
Formula	C₁₉H₁₂O₂
Cas No.	6051-87-2
Smiles	O=c1cc(oc2ccc3ccccc3c12)-c1ccccc1
Relative Density.	1.276g/cm3

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 15 mg/mL (55.08 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6724 mL	18.3621 mL	36.7242 mL	183.6210 mL
5 mM	0.7345 mL	3.6724 mL	7.3448 mL	36.7242 mL
10 mM	0.3672 mL	1.8362 mL	3.6724 mL	18.3621 mL
20 mM	0.1836 mL	0.9181 mL	1.8362 mL	9.1811 mL
50 mM	0.0734 mL	0.3672 mL	0.7345 mL	3.6724 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc