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Lats-IN-1

🥰Excellent
Catalog No. T9053Cas No. 1424635-83-5

Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.

Lats-IN-1

Lats-IN-1

🥰Excellent
Purity: 99.79%
Catalog No. T9053Cas No. 1424635-83-5
Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$48In StockIn Stock
5 mg$107In StockIn Stock
10 mg$170In StockIn Stock
25 mg$338In StockIn Stock
50 mg$438In StockIn Stock
100 mg$623In StockIn Stock
1 mL x 10 mM (in DMSO)$120In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.79%
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Product Introduction

Bioactivity
Description
Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.
Chemical Properties
Molecular Weight334.39
FormulaC18H14N4OS
Cas No.1424635-83-5
SmilesO=C(\N=c1/sccn1Cc1ccccc1)c1c[nH]c2ncccc12
Relative Density.1.36 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 83.33 mg/mL (249.20 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9905 mL14.9526 mL29.9052 mL149.5260 mL
5 mM0.5981 mL2.9905 mL5.9810 mL29.9052 mL
10 mM0.2991 mL1.4953 mL2.9905 mL14.9526 mL
20 mM0.1495 mL0.7476 mL1.4953 mL7.4763 mL
50 mM0.0598 mL0.2991 mL0.5981 mL2.9905 mL
100 mM0.0299 mL0.1495 mL0.2991 mL1.4953 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Yes-associated proteinYAPLats-IN-1LatsIN1Lats2Lats1Lats IN 1Inhibitorinhibit
Related Tags: buy Lats-IN-1 | purchase Lats-IN-1 | Lats-IN-1 cost | order Lats-IN-1 | Lats-IN-1 chemical structure | Lats-IN-1 formula | Lats-IN-1 molecular weight
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