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Anti-CD200RLa Antibody (7S310)

😃Good
Catalog No. TMAY-01943
Alias CD200RLa, CD200 receptor 1 like

Anti-CD200RLa Antibody (7S310) is a Rabbit antibody targeting CD200RLa. Anti-CD200RLa Antibody (7S310) can be used in ELISA(Cap).

Anti-CD200RLa Antibody (7S310)

Anti-CD200RLa Antibody (7S310)

😃Good
Catalog No. TMAY-01943Alias CD200RLa, CD200 receptor 1 like
Anti-CD200RLa Antibody (7S310) is a Rabbit antibody targeting CD200RLa. Anti-CD200RLa Antibody (7S310) can be used in ELISA(Cap).
Pack SizePriceAvailabilityQuantity
20 μL$94 7-10 days
100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-CD200RLa Antibody (7S310) is a Rabbit antibody targeting CD200RLa. Anti-CD200RLa Antibody (7S310) can be used in ELISA(Cap).
AliasCD200RLa, CD200 receptor 1 like
Ig Type
Monoclonal Rabbit IgG
Clone
7S310
Reactivity
Human
Application
ELISA(Cap)
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human CD200RLa (rh CD200RLa; TMPY-01591; AAT00538.1; Met1-Leu239).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCell surface glycoprotein CD2 receptor 2, also known as Cell surface glycoprotein CD2 receptor 1-like, Cell surface glycoprotein OX2 receptor 2, CD2 receptor-like 2, CD2Rla, CD2R1L and CD2R2, is a single-pass type I membrane protein which belongs to theCD2R family. CD2R1L / CD2R2. It contains oneIg-like C2-type (immunoglobulin-like) domain and oneIg-like V-type (immunoglobulin-like) domain. CD2 is a transmembrane protein delivering immunoregulatory signals after engagement of CD2R. A family of CD2Rs exist ( CD2R1, CD2R2, CD2R3, CD2R4 ) with different tissue expression and functional activity. In the presence of anti-CD2R2 / CD2R3 monoclonal antibodies (mAbs), bone-marrow cells cultured in the presence of (interleukin [IL]-4+granulocyte-macrophage colony-stimulating factor) differentiate into dendritic cells (DCs), which induce CD4+CD25+ Treg. Interaction between the relatively ubiquitously expressed molecule CD2 and one of its receptors, CD2R1, resulted in direct suppression of alloreactivity, engagement of alternate receptors led instead to altered differentiation of dendritic cells (DCs) from marrow precursors, which could in turn foster development of Foxp3(+) regulatory T cells. Unlike anti-CD2R1, anti-CD2R2 both promotes development of DCs with capacity to induce Treg and directly augments thymocyte production of Treg.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human CD200RLa Protein (TMPY-01591)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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