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Anti-DMBT1 Antibody (2Q307)
😃Good
Catalog No. TMAY-01984
Alias muclin, GP340, deleted in malignant brain tumors 1
Anti-DMBT1 Antibody (2Q307) is a Mouse antibody targeting DMBT1. Anti-DMBT1 Antibody (2Q307) can be used in ELISA.
Anti-DMBT1 Antibody (2Q307)
Anti-DMBT1 Antibody (2Q307)
😃Good
Catalog No. TMAY-01984Alias muclin, GP340, deleted in malignant brain tumors 1
Anti-DMBT1 Antibody (2Q307) is a Mouse antibody targeting DMBT1. Anti-DMBT1 Antibody (2Q307) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-DMBT1 Antibody (2Q307) is a Mouse antibody targeting DMBT1. Anti-DMBT1 Antibody (2Q307) can be used in ELISA. |
| Alias | muclin, GP340, deleted in malignant brain tumors 1 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 2Q307 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human DMBT1 / Muclin (rh DMBT1 / Muclin; TMPY-01442; NP_004397.2; Met 1-Ser 220). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are involved in the development of glioma (GLM). Gliomas are central nervous system neoplasms derived from glial cells and comprise astrocytomas, glioblastoma multiforme, oligodendrogliomas , and ependymomas. DMBT1 may be considered as a candidate tumor suppressor for brain, lung, esophageal, gastric, and colorectal cancers. It may play roles in mucosal defense system, cellular immune defense and epithelial differentiation. DMBT1 may play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. It may be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. DMBT1 may function as a binding protein in saliva for the regulation of taste sensation. It binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human DMBT1 / Muclin protein (TMPY-01442) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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