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RET-IN-1

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Catalog No. T16735Cas No. 2222755-14-6

RET-IN-1 is a RET kinase inhibitor with IC50 values of 1 nM for RET (WT), 7 nM for RET (V804M), and 101 nM for RET (G810R).

RET-IN-1

RET-IN-1

😃Good
Catalog No. T16735Cas No. 2222755-14-6
RET-IN-1 is a RET kinase inhibitor with IC50 values of 1 nM for RET (WT), 7 nM for RET (V804M), and 101 nM for RET (G810R).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$2,5303-6 months3-6 months
50 mg$3,4103-6 months3-6 months
100 mg$4,5303-6 months3-6 months
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
RET-IN-1 is a RET kinase inhibitor with IC50 values of 1 nM for RET (WT), 7 nM for RET (V804M), and 101 nM for RET (G810R).
Targets&IC50
RET (V804M):7 nM, RET (WT):1 nM, RET (G810R):101 nM
Chemical Properties
Molecular Weight553.61
FormulaC29H31N9O3
Cas No.2222755-14-6
SmilesC(#N)C1=C2C(=CC(OC[C@H]3CNCCO3)=CN2N=C1)C=4C=NC(=CN4)N5CC6N(CC=7C=CC(OC)=NC7)C(C5)C6
Relative Density.1.49 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

RETWTRETV804MRET-IN-1RETIN1RETG810RRET IN 1
Related Tags: buy RET-IN-1 | purchase RET-IN-1 | RET-IN-1 cost | order RET-IN-1 | RET-IN-1 chemical structure | RET-IN-1 formula | RET-IN-1 molecular weight
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