Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HDAC6 degrader-1, a proteolysis-targeting chimeric molecule (PROTAC), incorporates the selective HDAC6 inhibitor Nexturastat A (Nex A) for HDAC6 binding, a linker, and an E3 ligase recruiting ligand. This compound effectively induces HDAC6 degradation, displays superior selectivity over other HDAC isoforms, and efficiently inhibits cell proliferation [1].
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50 mg | Inquiry | Inquiry |
Description | HDAC6 degrader-1, a proteolysis-targeting chimeric molecule (PROTAC), incorporates the selective HDAC6 inhibitor Nexturastat A (Nex A) for HDAC6 binding, a linker, and an E3 ligase recruiting ligand. This compound effectively induces HDAC6 degradation, displays superior selectivity over other HDAC isoforms, and efficiently inhibits cell proliferation [1]. |
Molecular Weight | 795.84 |
Formula | C40H45N9O9 |
CAS No. | 2439058-23-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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HDAC6 degrader-1 2439058-23-6 PROTAC PROTACs inhibitor inhibit