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SDH-IN-3

Catalog No. T79238 CAS 2805297-11-2

SDH-IN-3 is a succinate dehydrogenase (SDH) inhibitor, demonstrating potent antifungal activity with an inhibition concentration (IC50) of 7.2 μg/mL and an effective concentration (EC50) of 1.9 μg/mL against Nigrospora oryzae. This compound is valuable for anti-infection research [1].

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SDH-IN-3, CAS 2805297-11-2

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Biological Description

Chemical Properties

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Description

In vitro

SDH-IN-3 (Compound T6) at a concentration of 40 μg/mL for 6-7 days exhibited a prophylactic effect of 81.5% and a curative effect of 43.0% against N. oryzae mycelia infection in rice [1]. Additionally, SDH-IN-3 in the range of 0-40 μg/mL over 14-80 hours significantly inhibited the growth of N. oryzae mycelia, as well as effectively impeding spore germination and germ tube elongation [1]. Furthermore, SDH-IN-3 at 0-20 μg/mL for 12-36 hours compromised the membrane integrity of N. oryzae mycelia by increasing cellular membrane permeability and causing lipid peroxidation [1].

Molecular Weight	319.33
Formula	C15H11F2N3OS
CAS No.	2805297-11-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

SDH-IN-3 2805297-11-2 Microbiology/Virology Antibiotic inhibitor inhibit

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