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Hydroxytyrosol Acetate (Synonyms: HTy-Ac)

Name: Hydroxytyrosol Acetate
Brand: TargetMol
SKU: T8168
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T8168 Copy Product Info

Purity: 99.97%

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Hydroxytyrosol Acetate (HTy-Ac) is found in the olive oil with antioxidant activity.

Hydroxytyrosol Acetate

Copy Product Info

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Catalog No. T8168

Synonyms HTy-Ac

Hydroxytyrosol Acetate (HTy-Ac) is found in the olive oil with antioxidant activity.

Cas No. 69039-02-7

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Pack Size	Price	USA Stock	Global Stock
10 mg	$40	In Stock	In Stock
25 mg	$73	In Stock	In Stock
50 mg	$108	In Stock	In Stock
100 mg	$163	In Stock	In Stock
200 mg	$243	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.97%

Appearance:Solid

Color:White to Yellow

Resource Download

COA HNMR HPLC

Product Introduction

Hydroxytyrosol Acetate AI Summary

Hydroxytyrosol Acetate exhibits diverse bioactivities, including antioxidant, antiviral, cytotoxic, anti-parasitic, and antiplatelet effects. It demonstrates significant antioxidant activity with a DPPH radical scavenging EC50 value of 0.57 µg/mL and can reduce iron-reactive oxidative stress by 36.0% in human HeLa cells. The compound has antiviral properties against viruses such as Poliovirus, Coxsackie virus, Herpes simplex virus types 1 and 2, Adenovirus types 2 and 5, and Cytomegalovirus, with ID50 values ranging from 20.0 to 50.0 µg/mL, though it also exhibits cytotoxicity towards African green monkey Vero cells, human Hep2, and HFF1 cells (CC50: 50.0 - 100.0 µg/mL). Regarding its cytotoxicity, Hydroxytyrosol Acetate causes 20.0% growth inhibition in human Caco2/TC7 cells at 5 µM and has an IC50 of 32,000.0 nM for the same cells after 24 hours. Additionally, it demonstrates an IC50 value greater than 50,000.0 nM against human MRC5 cells after 72 hours. It also shows antitrypanosomal activity (IC50: 43,400.0 nM) and inhibits 48.0% of Leishmania donovani axenic amastigotes at 20 µM after 72 hours. The compound inhibits collagen-induced platelet aggregation with an ID50 of 16.05 mg/kg/day in Wistar rats and an IC50 of 10,000.0 nM in human whole blood. It further inhibits A23187-induced TXA2 synthesis by 37.0% and NO production by 66.0% in Wistar rats over 7 days. Overall, Hydroxytyrosol Acetate exhibits a broad spectrum of bioactivities, making it potentially valuable for further pharmacological research..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Hydroxytyrosol Acetate (HTy-Ac) is found in the olive oil with antioxidant activity.
Synonyms	HTy-Ac

Chemical Properties

Molecular Weight	196.2
Formula	C₁₀H₁₂O₄
Cas No.	69039-02-7
Smiles	CC(=O)OCCc1ccc(O)c(O)c1
Relative Density.	1.26g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (229.36 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (25.48 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.0968 mL	25.4842 mL	50.9684 mL	254.8420 mL
5 mM	1.0194 mL	5.0968 mL	10.1937 mL	50.9684 mL
10 mM	0.5097 mL	2.5484 mL	5.0968 mL	25.4842 mL
20 mM	0.2548 mL	1.2742 mL	2.5484 mL	12.7421 mL
50 mM	0.1019 mL	0.5097 mL	1.0194 mL	5.0968 mL
100 mM	0.0510 mL	0.2548 mL	0.5097 mL	2.5484 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc