Shopping Cart
Remove All
Your shopping cart is currently empty
BUR1
Copy Product Info
🥰Excellent
Catalog No. T23840Cas No. 23000-46-6
Alias BUR-1, BUR 1, BMP upregulator-1, BMP upregulator 1
BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.
BUR1
Copy Product Info🥰Excellent
Catalog No. T23840Alias BUR-1, BUR 1, BMP upregulator-1, BMP upregulator 1Cas No. 23000-46-6
BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $132 | In Stock | In Stock | |
| 5 mg | $328 | In Stock | In Stock | |
| 10 mg | $496 | In Stock | In Stock | |
| 25 mg | $793 | In Stock | In Stock | |
| 50 mg | $1,120 | In Stock | - | |
| 1 mL x 10 mM (in DMSO) | $298 | In Stock | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Appearance:Solid
Color:White
Contact us for more batch information
Resource Download
Product Introduction
BUR1 AI Summary
BUR1 exhibits a diverse range of bioactivities, impacting numerous cellular pathways and processes. Key activities include the modulation and activation of miRNAs, notably miR-21, and the activation of the Rab9 and NPC1 promoters. It enhances SMN2 splice variant expression and inhibits tau fibril formation, ROR gamma transcriptional activity, aldehyde dehydrogenase 1 (ALDH1A1), Schistosoma mansoni peroxiredoxins, influenza NS1 protein function, 15-hydroxyprostaglandin dehydrogenase (HPGD), chronic active B-cell receptor signaling, ELG1-dependent DNA repair, malarial parasite plastids, HP1-beta chromodomain interactions, polymerase iota, TGF-beta, and cell surface uPA generation. Additionally, it modulates lipid storage in Drosophila S3 cells, induces genotoxicity in human embryonic kidney cells, activates p53, and modulates firefly luciferase activity. The compound also inhibits GLP-1 receptor activity, bursicon-induced LGR2 mediated cAMP production, and acts as a counterscreen in assays involving ROR gamma transcriptional activity and MC4R mediated in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells. These bioactivities collectively highlight BUR1's potential effects and applications in various biological research and therapeutic fields..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation. |
| Synonyms | BUR-1, BUR 1, BMP upregulator-1, BMP upregulator 1 |
| Molecular Weight | 279.34 |
| Formula | C16H17N5 |
| Cas No. | 23000-46-6 |
| Smiles | C1CCN(CC1)C1=NC=NC2=C1C=NN2C1=CC=CC=C1 |
| Relative Density. | 1.31 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (196.89 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy BUR1 | purchase BUR1 | BUR1 cost | order BUR1 | BUR1 chemical structure | BUR1 formula | BUR1 molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.