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BUR1

Name: BUR1
Brand: TargetMol
SKU: T23840
Price: 148 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T23840Cas No. 23000-46-6

Alias BUR-1, BUR 1, BMP upregulator-1, BMP upregulator 1

BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.

BUR1

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Catalog No. T23840Alias BUR-1, BUR 1, BMP upregulator-1, BMP upregulator 1Cas No. 23000-46-6

BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.

Pack Size	Price	Availability
1 mg	$148	In Stock
5 mg	$336	In Stock
10 mg	$497	In Stock
25 mg	$793	In Stock
50 mg	$1,130	In Stock
1 mL x 10 mM (in DMSO)	$318	In Stock

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Product Introduction

Bioactivity

Description	BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.
Synonyms	BUR-1, BUR 1, BMP upregulator-1, BMP upregulator 1

Chemical Properties

Molecular Weight	279.34
Formula	C₁₆H₁₇N₅
Cas No.	23000-46-6
Smiles	C1CCN(CC1)C1=NC=NC2=C1C=NN2C1=CC=CC=C1
Relative Density.	1.31 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (196.89 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5799 mL	17.8993 mL	35.7987 mL	178.9933 mL
5 mM	0.7160 mL	3.5799 mL	7.1597 mL	35.7987 mL
10 mM	0.3580 mL	1.7899 mL	3.5799 mL	17.8993 mL
20 mM	0.1790 mL	0.8950 mL	1.7899 mL	8.9497 mL
50 mM	0.0716 mL	0.3580 mL	0.7160 mL	3.5799 mL
100 mM	0.0358 mL	0.1790 mL	0.3580 mL	1.7899 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc