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Anti-IL-6R Antibody (6K916)

😃Good
Catalog No. TMAY-00762
Alias interleukin 6 receptor, IL6RQ, IL-6RA, IL6RA, IL-6R-1, IL-6R, IL6Q, gp80, CD126

Anti-IL-6R Antibody (6K916) is a Rabbit antibody targeting IL-6R. Anti-IL-6R Antibody (6K916) can be used in FCM.

Anti-IL-6R Antibody (6K916)

Anti-IL-6R Antibody (6K916)

😃Good
Catalog No. TMAY-00762Alias interleukin 6 receptor, IL6RQ, IL-6RA, IL6RA, IL-6R-1, IL-6R, IL6Q, gp80, CD126
Anti-IL-6R Antibody (6K916) is a Rabbit antibody targeting IL-6R. Anti-IL-6R Antibody (6K916) can be used in FCM.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-IL-6R Antibody (6K916) is a Rabbit antibody targeting IL-6R. Anti-IL-6R Antibody (6K916) can be used in FCM.
Aliasinterleukin 6 receptor, IL6RQ, IL-6RA, IL6RA, IL-6R-1, IL-6R, IL6Q, gp80, CD126
Ig Type
Monoclonal Rabbit IgG
Clone
6K916
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human IL-6R expression on U266 cells. Cells were stained with purified anti-Human IL-6R, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
FCM
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human IL-6R (rh IL-6R; TMPY-00864; NP_000556.1; Met1-Pro365).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundInterleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (SIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a SIL-6R protein can mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signaling. Through this so-called 'trans-signaling' mechanism, IL-6 can stimulate cells that lack an endogenous mIL-6R. High levels of IL-6 and SIL-6R have been reported in several chronic inflammatory and autoimmune diseases as well as in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Human IL-6R Protein (TMPY-00864)
Antigen Species
Human
Biology Area
Neuroinflammation
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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