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IC-1k is an effective inhibitor of HIV-1, exhibiting anti-viral activity with EC50 values of 2.69 nM against HIV-1IIIB and 97.97 nM against HIV-2 ROD. Additionally, IC-1k has been noted to possess cytotoxic properties.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
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| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | IC-1k is an effective inhibitor of HIV-1, exhibiting anti-viral activity with EC50 values of 2.69 nM against HIV-1IIIB and 97.97 nM against HIV-2 ROD. Additionally, IC-1k has been noted to possess cytotoxic properties. |
| Targets&IC50 | HIV-2 (ROD):97.97 nM (EC50), HIV-1 (IIIB):2.69 nM (EC50) |
| In vitro | IC-1k targets the HIV-1 capsid protein (CA), disrupting early capsid-host factor interactions and promoting the misassembly of the capsid during the later stages. |
| Molecular Weight | 520.55 |
| Formula | C27H22F2N4O3S |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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