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C18:1 Ceramide (d18:1/18:1(9Z))
🥰Excellent
Catalog No. T35808Cas No. 5966-28-9
Alias Cer(d18:1/18:1(9Z)), C18:1-Ceramide
C18:1 Ceramide (d18:1/18:1(9Z)) is a ceramide, and C18:1-Ceramide levels are elevated in overweight and insulin-resistant mice and cattle, as well as in plasma and ovarian tissue of patients with advanced ovarian cancer.
C18:1 Ceramide (d18:1/18:1(9Z))
🥰Excellent
Purity: 99.96%
Catalog No. T35808Alias Cer(d18:1/18:1(9Z)), C18:1-CeramideCas No. 5966-28-9
C18:1 Ceramide (d18:1/18:1(9Z)) is a ceramide, and C18:1-Ceramide levels are elevated in overweight and insulin-resistant mice and cattle, as well as in plasma and ovarian tissue of patients with advanced ovarian cancer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $36 | In Stock | |
| 5 mg | $80 | In Stock | |
| 10 mg | $128 | In Stock | |
| 25 mg | $257 | In Stock | |
| 50 mg | $410 | In Stock | |
| 100 mg | $655 | In Stock | |
| 200 mg | $990 | In Stock |
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Purity:99.96%
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Product Introduction
Bioactivity
Chemical Properties
| Description | C18:1 Ceramide (d18:1/18:1(9Z)) is a ceramide, and C18:1-Ceramide levels are elevated in overweight and insulin-resistant mice and cattle, as well as in plasma and ovarian tissue of patients with advanced ovarian cancer. |
| In vitro | Exogenous C18:1-Ceramide (5 μM, 24 h) significantly increased the survival of mouse primary retinal ganglion cells (RGCs) and reduced apoptosis induced by oxygen-glucose deprivation/reperfusion (OGD/R)[1]. |
| In vivo | Intravitreal injection of C18:1-Ceramide (1 μL, 10 μM) in a mouse optic nerve ischemia model improved structural integrity and reduced RGC apoptosis, supporting its neuroprotective potential in ischemic retinal injury[1]. |
| Alias | Cer(d18:1/18:1(9Z)), C18:1-Ceramide |
| Molecular Weight | 563.94 |
| Formula | C36H69NO3 |
| Cas No. | 5966-28-9 |
| Smiles | [C@@H](NC(CCCCCCC/C=C\CCCCCCCC)=O)([C@@H](/C=C/CCCCCCCCCCCCC)O)CO |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | keep away from direct sunlight | store at 4°C | Shipping with blue ice./Shipping at ambient temperature. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | DMF: 80 mg/mL (141.86 mM), Sonication is recommended. Chloroform: 4 mg/mL (7.09 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
Chloroform/DMF
DMF
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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