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Anti-Ferritin heavy chain 1/FTH1 Antibody (7Y790) is a Mouse antibody targeting Ferritin heavy chain 1/FTH1. Anti-Ferritin heavy chain 1/FTH1 Antibody (7Y790) can be used in ELISA.
Description | Anti-Ferritin heavy chain 1/FTH1 Antibody (7Y790) is a Mouse antibody targeting Ferritin heavy chain 1/FTH1. Anti-Ferritin heavy chain 1/FTH1 Antibody (7Y790) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 7Y790 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 50mM Hepes, 100mM NaCl. 10% Trehalose, 0.02% Tween80, pH7.5. |
Research Background | FTH1 (ferritin, heavy polypeptide 1) is the heavy subunit of ferritin which is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. FTH1 gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. FTH1 stores iron in a soluble, non-toxic, readily available form. It is important for iron homeostasis. It has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. It also plays a role in delivery of iron to cells. FTH1 mediates iron uptake in capsule cells of the developing kidney. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human Ferritin heavy chain 1 / FTH1 Protein (TMPY-02711) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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