Shopping Cart
Remove All
Your shopping cart is currently empty
Cixutumumab
😃Good
Catalog No. T78279Cas No. 947687-12-9
Alias NSC742460, NSC 742460, LY3012217, LY 3012217, IMC-A12, IMCA12
Cixutumumab (IMC-A12) is a humanized IgG monoclonal antibody targeting the insulin-like growth factor 1 receptor (IGF1R). It has anticancer activity, inhibits ligand-dependent receptor activation and downstream signaling, and can be used in the study of non-small cell lung and prostate cancer.
Cixutumumab
Cixutumumab
😃Good
Catalog No. T78279Alias NSC742460, NSC 742460, LY3012217, LY 3012217, IMC-A12, IMCA12Cas No. 947687-12-9
Cixutumumab (IMC-A12) is a humanized IgG monoclonal antibody targeting the insulin-like growth factor 1 receptor (IGF1R). It has anticancer activity, inhibits ligand-dependent receptor activation and downstream signaling, and can be used in the study of non-small cell lung and prostate cancer.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $118 | - | In Stock | |
| 5 mg | $328 | - | In Stock | |
| 10 mg | $529 | - | In Stock | |
| 25 mg | $843 | - | In Stock | |
| 50 mg | $1,130 | - | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:98.5% (SDS-PAGE); 97.5% (SEC-HPLC)
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Cixutumumab (IMC-A12) is a humanized IgG monoclonal antibody targeting the insulin-like growth factor 1 receptor (IGF1R). It has anticancer activity, inhibits ligand-dependent receptor activation and downstream signaling, and can be used in the study of non-small cell lung and prostate cancer. |
| In vitro | Cixutumumab showed significant growth inhibition of at least 50% in CHLA-9, TC-71 and Rh41 cell lines after 96 hours of treatment at concentrations ranging from 0.01 to 100 nM. [1] |
| In vivo | In an in vivo model of the Pediatric Preclinical Testing Program (PPTP), Cixutumumab, given to rats by intraperitoneal injection at a dose of 1 mg twice weekly for six weeks, showed potent antitumor effects and significantly inhibited the progression of solid tumors. [1] |
| Synonyms | NSC742460, NSC 742460, LY3012217, LY 3012217, IMC-A12, IMCA12 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | IGF1-R/IGFR1/CD221 |
| Molecular Weight | 146.32 kDa |
| Cas No. | 947687-12-9 |
| Isotype | IgG1 |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Cixutumumab | purchase Cixutumumab | Cixutumumab cost | order Cixutumumab | Cixutumumab in vivo | Cixutumumab in vitro | Cixutumumab molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.