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6,7-dimethylisatin

Name: 6,7-dimethylisatin
Brand: TargetMol
SKU: T77568
Price: 82 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T77568Cas No. 20205-43-0

Alias 6,7-dimethyl-1H-indole-2,3-dione

6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.

6,7-dimethylisatin

🥰Excellent

Purity: 98.98%

Catalog No. T77568Alias 6,7-dimethyl-1H-indole-2,3-dioneCas No. 20205-43-0

6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.

Pack Size	Price	Availability
1 mg	$82	In Stock
5 mg	$181	In Stock
10 mg	$267	In Stock
25 mg	$413	In Stock
50 mg	$592	In Stock
100 mg	$819	In Stock
200 mg	$1,090	In Stock

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Batch Information

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Purity:98.98%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.
Targets&IC50	MAO-A:20.3 μM, MAO-B:6.74 μM
Synonyms	6,7-dimethyl-1H-indole-2,3-dione

Chemical Properties

Molecular Weight	175.18
Formula	C₁₀H₉NO₂
Cas No.	20205-43-0
Smiles	CC1=C(C)C2=C(C=C1)C(=O)C(=O)N2

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (285.42 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.7084 mL	28.5421 mL	57.0841 mL	285.4207 mL
5 mM	1.1417 mL	5.7084 mL	11.4168 mL	57.0841 mL
10 mM	0.5708 mL	2.8542 mL	5.7084 mL	28.5421 mL
20 mM	0.2854 mL	1.4271 mL	2.8542 mL	14.2710 mL
50 mM	0.1142 mL	0.5708 mL	1.1417 mL	5.7084 mL
100 mM	0.0571 mL	0.2854 mL	0.5708 mL	2.8542 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc