Powder: -20°C for 3 years | In solvent: -80°C for 1 year
WCA-814, an androgen receptor (AR) antagonist-Hsp90 inhibitor conjugate, induces degradation of both full-length and AR-V7, exhibiting cytotoxic effects in prostatic cancer cells with half maximal inhibitory concentrations (IC50) of 171.2 nM and 26.5 nM for LNCaP and 22Rv1 cells, respectively [1].
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Description | WCA-814, an androgen receptor (AR) antagonist-Hsp90 inhibitor conjugate, induces degradation of both full-length and AR-V7, exhibiting cytotoxic effects in prostatic cancer cells with half maximal inhibitory concentrations (IC50) of 171.2 nM and 26.5 nM for LNCaP and 22Rv1 cells, respectively [1]. |
Molecular Weight | 861.43 |
Formula | C46H53ClN10O5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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WCA-814 Endocrinology/Hormones Androgen Receptor inhibitor inhibit