Shopping Cart

Remove All
Your shopping cart is currently empty

CID 2745687

Name: CID 2745687
Brand: TargetMol
SKU: T21874
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T21874Cas No. 264233-05-8

CID 2745687 is a moderately potent, concentration-dependent antagonist at human GPR35 with pIC50 = 6.70. CID 2745687 cannot effectively antagonize the agonist effects of either Zaprinast or Cromolyn disodium at rodent ortholog of GPR35 in vitro[1]. However, CID 2745687 can reverse lodoxamide-mediated anti-fibrotic effects in mice in vivo[2].

CID 2745687

🥰Excellent

Purity: 99.11%

Catalog No. T21874Cas No. 264233-05-8

Pack Size	Price	Availability
1 mg	$34	In Stock
2 mg	$48	In Stock
5 mg	$80	In Stock
10 mg	$128	In Stock
25 mg	$289	In Stock
50 mg	$455	In Stock
100 mg	$672	In Stock
1 mL x 10 mM (in DMSO)	$89	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.11%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	395.43
Formula	C₁₇H₁₉F₂N₅O₂S
Cas No.	264233-05-8
Smiles	COC(=O)c1cnn(c1C=NNC(=S)NC(C)(C)C)-c1ccc(F)cc1F
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (151.73 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5289 mL	12.6445 mL	25.2889 mL	126.4446 mL
5 mM	0.5058 mL	2.5289 mL	5.0578 mL	25.2889 mL
10 mM	0.2529 mL	1.2644 mL	2.5289 mL	12.6445 mL
20 mM	0.1264 mL	0.6322 mL	1.2644 mL	6.3222 mL
50 mM	0.0506 mL	0.2529 mL	0.5058 mL	2.5289 mL
100 mM	0.0253 mL	0.1264 mL	0.2529 mL	1.2644 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc