Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LEB-03-146, a WEE1 DUBTAC (deubiquitinase-targeting chimera), effectively links AZD1775 (Adavosertib) with the OTUB1 recruiter EN523 via a PEG2 linker. This compound demonstrates considerable WEE1 stabilization in HEP3B hepatoma cancer cells [1].
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Description | LEB-03-146, a WEE1 DUBTAC (deubiquitinase-targeting chimera), effectively links AZD1775 (Adavosertib) with the OTUB1 recruiter EN523 via a PEG2 linker. This compound demonstrates considerable WEE1 stabilization in HEP3B hepatoma cancer cells [1]. |
Molecular Weight | 892.01 |
Formula | C46H57N11O8 |
CAS No. | 2858812-91-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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LEB-03-146 2858812-91-4 inhibitor inhibit