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Solitomab
(Synonyms: AMG-110, AMG110, AMG 110) Copy Product Info
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Synonyms: AMG-110, AMG110, AMG 110
Catalog No. T76996 Copy Product Info
Purity: 95%
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Solitomab (AMG 110) is a bispecific single-chain antibody targeting CD3 and EpCAM/CD326 (epithelial cell adhesion molecule), exhibiting in vitro activity against primary uterine carcinoma and ovarian sarcoma cell lines.
Solitomab
Cas No. 1005198-65-1
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $668 | - | In Stock | |
| 5 mg | $1,350 | - | In Stock | |
| 10 mg | $1,820 | - | In Stock | |
| 25 mg | $2,710 | - | In Stock | |
| 50 mg | $3,660 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95%
Appearance:Liquid
Color:Transparent
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Product Introduction
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| Description | Solitomab (AMG 110) is a bispecific single-chain antibody targeting CD3 and EpCAM/CD326 (epithelial cell adhesion molecule), exhibiting in vitro activity against primary uterine carcinoma and ovarian sarcoma cell lines. |
| In vitro | Solitomab (1 μg/mL; 4 h) exhibits cytotoxicity toward EpCAM-positive cell lines, enhances sensitivity of EpCAM-positive sarcoma (CS) cells to T-cell-mediated cytotoxicity, and increases surface expression of CD25 and HLA-DR proteins on CD8+ and CD4+ T cells [1]. Solitomab (0–2.5 μg/mL; 4 hours) exhibits cytotoxicity against ovarian cancer cells, with optimal killing effect at 1 μg/mL [2]. |
| Synonyms | AMG-110, AMG110, AMG 110 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | CD3/EpCAM |
| Molecular Weight | 53.94 kDa |
| Cas No. | 1005198-65-1 |
| Isotype | Rat IgG2a kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Solitomab in vitro | Solitomab molecular weight
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