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TOPBioactivityChemical infoStorage&SolubilityCalculator

A-943931 (hydrochloride hydrate)

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Catalog No. T38323

A-943931 is a histamine H4receptor antagonist (Ki= 3.8 nM).1

A-943931 (hydrochloride hydrate)
Other Forms of A-943931 (hydrochloride hydrate):

A-943931 (hydrochloride hydrate)

😃Good
Catalog No. T38323
A-943931 is a histamine H4receptor antagonist (Ki= 3.8 nM).1
Pack SizePriceAvailabilityQuantity
1 mgTBD35 days
5 mgTBD35 days
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Product Introduction

Bioactivity
Description
A-943931 is a histamine H4receptor antagonist (Ki= 3.8 nM).1
In vivo
In vivo, A-943931 inhibits scratching induced by clobenpropit in mice (ED50= 26 μmoles/kg, i.p.).
Chemical Properties
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 100 mM, Sonication is recommended.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

A943931hydrochloride HydrateA-943931A 943931 (hydrochloride hydrate)A 943931A943931 (hydrochloride hydrate)
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