Shopping Cart

Your shopping cart is currently empty

GS-9901

Name: GS-9901
Brand: TargetMol
SKU: T15420
Price: 84 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T15420Cas No. 1640247-87-5

GS-9901 is a selective, orally active and potent PI3Kδ inhibitor (IC50: 1 nM) for the study of non-Hodgkin's lymphoma and chronic lymphocytic leukemia.

GS-9901

🥰Excellent

Purity: 99.92%

Catalog No. T15420Cas No. 1640247-87-5

GS-9901 is a selective, orally active and potent PI3Kδ inhibitor (IC50: 1 nM) for the study of non-Hodgkin's lymphoma and chronic lymphocytic leukemia.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$84	In Stock	In Stock
5 mg	$198	In Stock	In Stock
10 mg	$347	In Stock	In Stock
25 mg	$745	In Stock	In Stock
50 mg	$987	In Stock	In Stock
100 mg	$1,370	In Stock	In Stock
500 mg	$2,760	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

Questions

Batch Information

Select Batch

Purity:99.92%

ee:100%

Resource Download

COA CSFC FNMR HNMR LCMS

Product Introduction

Bioactivity

Description	GS-9901 is a selective, orally active and potent PI3Kδ inhibitor (IC50: 1 nM) for the study of non-Hodgkin's lymphoma and chronic lymphocytic leukemia.
Targets&IC50	PI3Kδ:1 nM
In vivo	In female Lewis rats with established collagen-induced arthritis (CIA), GS-9901 (0.3 mg/kg, 1 mg/kg, and 3 mg/kg; orally, twice daily for 7 days starting on the 10th day after the second collagen immunization) significantly reduced ankle swelling[1].

Chemical Properties

Molecular Weight	477.88
Formula	C₂₂H₁₇ClFN₉O
Cas No.	1640247-87-5
Smiles	[C@@H](NC=1C(C#N)=C(N)N=C(N)N1)(C=2N(C(=O)C=3C(N2)=C(F)C=CC3Cl)C=4C=CC=NC4)C5CC5
Relative Density.	1.71 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 120 mg/mL (251.11 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0926 mL	10.4629 mL	20.9258 mL	104.6288 mL
5 mM	0.4185 mL	2.0926 mL	4.1852 mL	20.9258 mL
10 mM	0.2093 mL	1.0463 mL	2.0926 mL	10.4629 mL
20 mM	0.1046 mL	0.5231 mL	1.0463 mL	5.2314 mL
50 mM	0.0419 mL	0.2093 mL	0.4185 mL	2.0926 mL
100 mM	0.0209 mL	0.1046 mL	0.2093 mL	1.0463 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc