Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ANO1-IN-1, a selective ANO1 channel blocker, inhibited ANO1 and ANO2 with IC50 values of 2.56 μM and 15.43 μM, respectively.ANO1-IN-1 had a significant inhibitory effect on the proliferation of glioma cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 39.00 | |
10 mg | In stock | $ 55.00 | |
25 mg | In stock | $ 118.00 | |
50 mg | In stock | $ 189.00 | |
100 mg | In stock | $ 278.00 |
Description | ANO1-IN-1, a selective ANO1 channel blocker, inhibited ANO1 and ANO2 with IC50 values of 2.56 μM and 15.43 μM, respectively.ANO1-IN-1 had a significant inhibitory effect on the proliferation of glioma cells. |
Targets&IC50 | ANO1:2.56 μM, ANO2:15.43 μM |
In vitro |
ANO1-IN-1 (Compound 9c) (10 μM) exerts a marked inhibitory effect on the migration and invasion of U251 cells.[1] ANO1-IN-1 and TMZ combination brings about remarkable synergistic effects in suppressing the proliferation of GBM cells.[1] |
Molecular Weight | 336.49 |
Formula | C18H28N2O2S |
CAS No. | 407587-01-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 225.0 mg/mL (668.7 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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ANO1-IN-1 407587-01-3 Membrane transporter/Ion channel Chloride channel inhibitor inhibit