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Anti-ETHE1 Antibody (9J276) (Synonyms: YF13H12, HSCO, ethylmalonic encephalopathy 1)

Catalog No. TMAY-02768 Copy Product Info
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Anti-ETHE1 Antibody (9J276) is a Rabbit antibody targeting ETHE1. Anti-ETHE1 Antibody (9J276) can be used in ELISA.

Anti-ETHE1 Antibody (9J276)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02768
Synonyms YF13H12, HSCO, ethylmalonic encephalopathy 1

Anti-ETHE1 Antibody (9J276) is a Rabbit antibody targeting ETHE1. Anti-ETHE1 Antibody (9J276) can be used in ELISA.

Anti-ETHE1 Antibody
(9J276)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ETHE1 Antibody (9J276) is a Rabbit antibody targeting ETHE1. Anti-ETHE1 Antibody (9J276) can be used in ELISA.
SynonymsYF13H12, HSCO, ethylmalonic encephalopathy 1
Ig Type
Rabbit IgG
Clone
9J276
Reactivity
Human
Specificity
Human ETHE1
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human ETHE1 / HSCO (rh ETHE1 / HSCO; TMPY-03658; O95571; Leu13-Ala254).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundETHE1, also known as HSCO, is a sulfur dioxygenase that localizes within the mitochondrial matrix. ETHE1 probably plays an important role in metabolic homeostasis in mitochondria. It may also function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytoplasm. ETHE1 can suppresses p53-induced apoptosis by preventing nuclear localization of RELA. Mutations in ETHE1 gene result in ethylmalonic encephalopathy. Ethylmalonic encephalopathy is an autosomal recessive, invariably fatal disorder characterized by early-onset encephalopathy, microangiopathy, chronic diarrhea, defective cytochrome c oxidase (COX) in muscle and brain, high concentrations of C4 and C5 acylcarnitines in blood and high excretion of ethylmalonic acid in urine.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human ETHE1 / HSCO Protein (TMPY-03658)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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