Shopping Cart
- Remove All
- Your shopping cart is currently empty
Anti-ETHE1 Antibody (9J276) is a Rabbit antibody targeting ETHE1. Anti-ETHE1 Antibody (9J276) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-ETHE1 Antibody (9J276) is a Rabbit antibody targeting ETHE1. Anti-ETHE1 Antibody (9J276) can be used in ELISA. |
Alias | YF13H12, HSCO, ethylmalonic encephalopathy 1 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 9J276 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ETHE1 / HSCO (rh ETHE1 / HSCO; TMPY-03658; O95571; Leu13-Ala254). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | ETHE1, also known as HSCO, is a sulfur dioxygenase that localizes within the mitochondrial matrix. ETHE1 probably plays an important role in metabolic homeostasis in mitochondria. It may also function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytoplasm. ETHE1 can suppresses p53-induced apoptosis by preventing nuclear localization of RELA. Mutations in ETHE1 gene result in ethylmalonic encephalopathy. Ethylmalonic encephalopathy is an autosomal recessive, invariably fatal disorder characterized by early-onset encephalopathy, microangiopathy, chronic diarrhea, defective cytochrome c oxidase (COX) in muscle and brain, high concentrations of C4 and C5 acylcarnitines in blood and high excretion of ethylmalonic acid in urine. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human ETHE1 / HSCO Protein (TMPY-03658) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.