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1H-1-ethyl Candesartan Cilexetil

🥰Excellent
Catalog No. T21591Cas No. 914613-35-7

1H-1-ethyl Candesartan Cilexetil is a process-related impurity in the bulk synthesis of candesartan cilexetil, which is a potent, long-acting and selective angiotensin II type 1 receptor (AT1) antagonist.

1H-1-ethyl Candesartan Cilexetil

1H-1-ethyl Candesartan Cilexetil

🥰Excellent
Purity: 98.19%
Catalog No. T21591Cas No. 914613-35-7
1H-1-ethyl Candesartan Cilexetil is a process-related impurity in the bulk synthesis of candesartan cilexetil, which is a potent, long-acting and selective angiotensin II type 1 receptor (AT1) antagonist.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$35In StockIn Stock
2 mg$62In StockIn Stock
5 mg$136In StockIn Stock
10 mg$198In StockIn Stock
25 mg$346In StockIn Stock
50 mg$496In StockIn Stock
100 mg$678In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.19%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
1H-1-ethyl Candesartan Cilexetil is a process-related impurity in the bulk synthesis of candesartan cilexetil, which is a potent, long-acting and selective angiotensin II type 1 receptor (AT1) antagonist.
Chemical Properties
Molecular Weight638.71
FormulaC35H38N6O6
Cas No.914613-35-7
SmilesC(N1C=2C(N=C1OCC)=CC=CC2C(OC(OC(OC3CCCCC3)=O)C)=O)C4=CC=C(C=C4)C5=C(C=CC=C5)C=6N(CC)N=NN6
Relative Density.1.32 g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (70.45 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5657 mL7.8283 mL15.6566 mL78.2828 mL
5 mM0.3131 mL1.5657 mL3.1313 mL15.6566 mL
10 mM0.1566 mL0.7828 mL1.5657 mL7.8283 mL
20 mM0.0783 mL0.3914 mL0.7828 mL3.9141 mL
50 mM0.0313 mL0.1566 mL0.3131 mL1.5657 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

InhibitorinhibitCandesartan Cilexetil1H-1-ethyl Candesartan Cilexetil1H1ethyl Candesartan Cilexetil1H 1 ethyl Candesartan Cilexetil
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