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Neochamaejasmine B

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Catalog No. TN1977Cas No. 90411-12-4

Neochamaejasmine B displays nematicidal activity against both Bursaphelenchus xylophilus and Bursaphelenchus mucronatus.

Neochamaejasmine B

Neochamaejasmine B

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🥰Excellent
Purity: 99.89%
Catalog No. TN1977Cas No. 90411-12-4
Neochamaejasmine B displays nematicidal activity against both Bursaphelenchus xylophilus and Bursaphelenchus mucronatus.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$133In StockIn Stock
2 mg$197In StockIn Stock
5 mg$297In StockIn Stock
10 mg$447In StockIn Stock
25 mg$738In StockIn Stock
50 mg$987In StockIn Stock
1 mL x 10 mM (in DMSO)$392In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.89%
Appearance:Solid
Color:White to Yellow
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Product Introduction

Bioactivity
Description
Neochamaejasmine B displays nematicidal activity against both Bursaphelenchus xylophilus and Bursaphelenchus mucronatus.
In vitro
In this field, Stellera chamaejasme L. (Thymelaeaceae) is one of the most toxic and ecologically-threatening weeds in some of the grasslands of north and west China. Bioassay-guided fractionation of root extracts of this plant led to the isolation of eight flavonoids 1-8, whose structures were elucidated by spectroscopic analysis. All compounds obtained, except 7-methoxylneochaejasmin A (4) and (+)-epiafzelechin (5), showed strong phytotoxic activity against Arabidopsis thaliana seedlings. Seedling growth was reduced by neochamaejasmin B (Neochamaejasmine B,1), mesoneochamaejasmin A (2), chamaejasmenin C (3), genkwanol A (6), daphnodorin B (7) and dihydrodaphnodorin B (8) with IC50 values of 6.9, 12.1, 43.2, 74.8, 7.1 and 27.3μg/mL, respectively, and all of these compounds disrupted root development[1]
Chemical Properties
Molecular Weight542.49
FormulaC30H22O10
Cas No.90411-12-4
SmilesO=C1[C@]([C@@H](OC=2C1=C(O)C=C(O)C2)C3=CC=C(O)C=C3)([C@]4([C@H](OC=5C(C4=O)=C(O)C=C(O)C5)C6=CC=C(O)C=C6)[H])[H]
Relative Density.1.594 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 65 mg/mL (119.82 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8434 mL9.2168 mL18.4335 mL92.1676 mL
5 mM0.3687 mL1.8434 mL3.6867 mL18.4335 mL
10 mM0.1843 mL0.9217 mL1.8434 mL9.2168 mL
20 mM0.0922 mL0.4608 mL0.9217 mL4.6084 mL
50 mM0.0369 mL0.1843 mL0.3687 mL1.8434 mL
100 mM0.0184 mL0.0922 mL0.1843 mL0.9217 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Stellera chamaejasmeNeochamaejasmine BNeochamaejasmin BInhibitorinhibitcis-trans geometrybiflavanoneAntifection(+)-Neochamaejasmin B
Related Tags: buy Neochamaejasmine B | purchase Neochamaejasmine B | Neochamaejasmine B cost | order Neochamaejasmine B | Neochamaejasmine B chemical structure | Neochamaejasmine B in vitro | Neochamaejasmine B formula | Neochamaejasmine B molecular weight
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