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Alkynyl myristic acid

Name: Alkynyl myristic acid
Brand: TargetMol
SKU: T14184
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T14184Cas No. 82909-47-5

Alias tetradec-13-ynoic acid, 13-Tetradecynoic acid, 13-Tetradecyn-1-oic acid

Alkynyl myristic acid (13-Tetradecyn-1-oic acid) is an alkyl chain-based PROTAC linker.

Alkynyl myristic acid

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Purity: 95.61%

Catalog No. T14184Alias tetradec-13-ynoic acid, 13-Tetradecynoic acid, 13-Tetradecyn-1-oic acidCas No. 82909-47-5

Alkynyl myristic acid (13-Tetradecyn-1-oic acid) is an alkyl chain-based PROTAC linker.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$31	-	In Stock
10 mg	$46	-	In Stock
25 mg	$95	-	In Stock
50 mg	$158	-	In Stock
100 mg	$238	-	In Stock
200 mg	$353	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:95.61%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Alkynyl myristic acid (13-Tetradecyn-1-oic acid) is an alkyl chain-based PROTAC linker.
In vitro	PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Synonyms	tetradec-13-ynoic acid, 13-Tetradecynoic acid, 13-Tetradecyn-1-oic acid

Chemical Properties

Molecular Weight	224.34
Formula	C₁₄H₂₄O₂
Cas No.	82909-47-5
Smiles	C(CCCCCCC#C)CCCCC(O)=O
Relative Density.	0.9192 g/cm3 (Estimated)
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (401.18 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Saline: 3.3 mg/mL (14.71 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4575 mL	22.2876 mL	44.5752 mL	222.8760 mL
5 mM	0.8915 mL	4.4575 mL	8.9150 mL	44.5752 mL
10 mM	0.4458 mL	2.2288 mL	4.4575 mL	22.2876 mL
20 mM	0.2229 mL	1.1144 mL	2.2288 mL	11.1438 mL
50 mM	0.0892 mL	0.4458 mL	0.8915 mL	4.4575 mL
100 mM	0.0446 mL	0.2229 mL	0.4458 mL	2.2288 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc