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Alkynyl myristic acid

🥰Excellent
Catalog No. T14184Cas No. 82909-47-5
Alias tetradec-13-ynoic acid, 13-Tetradecynoic acid, 13-Tetradecyn-1-oic acid

Alkynyl myristic acid (13-Tetradecyn-1-oic acid) is an alkyl chain-based PROTAC linker.

Alkynyl myristic acid

Alkynyl myristic acid

🥰Excellent
Purity: 95.61%
Catalog No. T14184Alias tetradec-13-ynoic acid, 13-Tetradecynoic acid, 13-Tetradecyn-1-oic acidCas No. 82909-47-5
Alkynyl myristic acid (13-Tetradecyn-1-oic acid) is an alkyl chain-based PROTAC linker.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$31-In Stock
10 mg$46-In Stock
25 mg$95-In Stock
50 mg$158-In Stock
100 mg$238-In Stock
200 mg$353-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:95.61%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
Alkynyl myristic acid (13-Tetradecyn-1-oic acid) is an alkyl chain-based PROTAC linker.
In vitro
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Synonymstetradec-13-ynoic acid, 13-Tetradecynoic acid, 13-Tetradecyn-1-oic acid
Chemical Properties
Molecular Weight224.34
FormulaC14H24O2
Cas No.82909-47-5
SmilesC(CCCCCCC#C)CCCCC(O)=O
Relative Density.0.9192 g/cm3 (Estimated)
ColorYellow
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 90 mg/mL (401.2 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.4575 mL22.2876 mL44.5752 mL222.8760 mL
5 mM0.8915 mL4.4575 mL8.9150 mL44.5752 mL
10 mM0.4458 mL2.2288 mL4.4575 mL22.2876 mL
20 mM0.2229 mL1.1144 mL2.2288 mL11.1438 mL
50 mM0.0892 mL0.4458 mL0.8915 mL4.4575 mL
100 mM0.0446 mL0.2229 mL0.4458 mL2.2288 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PROTACLinkerPROTAC LinkerAlkynyl myristic acidAlkyl-Chain
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