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Frexalimab (Synonyms: SAR-441344, SAR441344, INX-021, INX021)
Catalog No. T77013 Copy Product Info
Purity: 95%
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Frexalimab (SAR441344) is a second-generation humanized monoclonal antibody targeting CD40L. It blocks the CD40/CD40L signaling pathway to reduce inflammation and tissue damage, making it applicable for autoimmune diseases such as primary Sjögren's syndrome, systemic lupus erythematosus, and multiple sclerosis.
Frexalimab
Copy Product Info🥰Excellent
Catalog No. T77013
Synonyms SAR-441344, SAR441344, INX-021, INX021
Frexalimab (SAR441344) is a second-generation humanized monoclonal antibody targeting CD40L. It blocks the CD40/CD40L signaling pathway to reduce inflammation and tissue damage, making it applicable for autoimmune diseases such as primary Sjögren's syndrome, systemic lupus erythematosus, and multiple sclerosis.
Frexalimab
Cas No. 2515463-86-0
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $328 | - | In Stock | |
| 5 mg | $859 | - | In Stock | |
| 10 mg | $1,380 | - | In Stock | |
| 25 mg | $1,980 | - | In Stock | |
| 50 mg | $2,760 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95%
Appearance:Liquid
Color:Transparent
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| Description | Frexalimab (SAR441344) is a second-generation humanized monoclonal antibody targeting CD40L. It blocks the CD40/CD40L signaling pathway to reduce inflammation and tissue damage, making it applicable for autoimmune diseases such as primary Sjögren's syndrome, systemic lupus erythematosus, and multiple sclerosis. |
| In vitro | Frexalimab is a second-generation Fc-modified humanized monoclonal antibody against CD40L, whose Fc modification eliminates platelet activation triggered by immune complex stimulation of FcγRIIa [2]. |
| Synonyms | SAR-441344, SAR441344, INX-021, INX021 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | CD40 |
| Cas No. | 2515463-86-0 |
| Isotype | IgG1-ARA |
| Storage | Store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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