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Frexalimab
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Catalog No. T77013Cas No. 2515463-86-0
Alias SAR-441344, SAR441344, INX-021, INX021
Frexalimab (SAR441344) is a second-generation humanized monoclonal antibody targeting CD40L. It blocks the CD40/CD40L signaling pathway to reduce inflammation and tissue damage, making it applicable for autoimmune diseases such as primary Sjögren's syndrome, systemic lupus erythematosus, and multiple sclerosis.
Frexalimab
Frexalimab
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Purity: 95%
Catalog No. T77013Alias SAR-441344, SAR441344, INX-021, INX021Cas No. 2515463-86-0
Frexalimab (SAR441344) is a second-generation humanized monoclonal antibody targeting CD40L. It blocks the CD40/CD40L signaling pathway to reduce inflammation and tissue damage, making it applicable for autoimmune diseases such as primary Sjögren's syndrome, systemic lupus erythematosus, and multiple sclerosis.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $328 | - | In Stock | |
| 5 mg | $859 | - | In Stock | |
| 10 mg | $1,380 | - | In Stock | |
| 25 mg | $1,980 | - | In Stock | |
| 50 mg | $2,760 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95%
Appearance:Liquid
Color:Transparent
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| Description | Frexalimab (SAR441344) is a second-generation humanized monoclonal antibody targeting CD40L. It blocks the CD40/CD40L signaling pathway to reduce inflammation and tissue damage, making it applicable for autoimmune diseases such as primary Sjögren's syndrome, systemic lupus erythematosus, and multiple sclerosis. |
| In vitro | Frexalimab is a second-generation Fc-modified humanized monoclonal antibody against CD40L, whose Fc modification eliminates platelet activation triggered by immune complex stimulation of FcγRIIa [2]. |
| Synonyms | SAR-441344, SAR441344, INX-021, INX021 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | CD40 |
| Cas No. | 2515463-86-0 |
| Isotype | IgG1-ARA |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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