Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa, thereby inhibiting its activity.Asundexian has an IC50 of 1 nM for human FXIa in buffer.Asundexian has antitumor activity and may be useful in studies of Acute ischemic stroke, transient ischemic attack and ischemic stroke.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 188.00 | |
5 mg | In stock | $ 478.00 | |
10 mg | In stock | $ 720.00 | |
25 mg | In stock | $ 1,230.00 | |
50 mg | In stock | $ 1,860.00 | |
100 mg | In stock | $ 2,820.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 528.00 |
Description | Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa, thereby inhibiting its activity.Asundexian has an IC50 of 1 nM for human FXIa in buffer.Asundexian has antitumor activity and may be useful in studies of Acute ischemic stroke, transient ischemic attack and ischemic stroke. |
Targets&IC50 | FXIa (human):1 nM |
In vivo | Asundexian displays potent anticoagulant activity in vitro in human and rabbit plasma and antithrombotic efficacy in vivo in a rabbit arterial thrombosis model.[1] |
Synonyms | BAY 2433334, Asundexian, BAY2433334, BAY-2433334 |
Molecular Weight | 592.93 |
Formula | C26H21ClF4N6O4 |
CAS No. | 2064121-65-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 118.59 mg/mL (200 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Asundexian 2064121-65-7 Metabolism Factor Xa BAY 2433334 BAY2433334 BAY-2433334 inhibitor inhibit