Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Anticancer agent 136 (compound 22), a C17-triazole analogue of Geldanamycin (GDM), exhibits an IC50 value of 3.38 μM against human dermal fibroblasts (HDF) and binds to Heat shock protein 90 (Hsp90) with a dissociation constant (Kd) of 3.86 μM, demonstrating its apoptosis-inducing capabilities [1].
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Description | Anticancer agent 136 (compound 22), a C17-triazole analogue of Geldanamycin (GDM), exhibits an IC50 value of 3.38 μM against human dermal fibroblasts (HDF) and binds to Heat shock protein 90 (Hsp90) with a dissociation constant (Kd) of 3.86 μM, demonstrating its apoptosis-inducing capabilities [1]. |
Molecular Weight | 742.86 |
Formula | C40H50N6O8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Anticancer agent 136 Apoptosis inhibitor inhibit