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1-Octanol

🥰Excellent
Catalog No. T10024Cas No. 111-87-5
Alias Octanol

1-Octanol, a saturated fatty alcohol, functions as an inhibitor of T-type calcium channels (T-channels), showing an inhibitory concentration (IC50) of 4 μM for native T-currents[1]. Additionally, 1-Octanol is recognized for its potential as a biofuel, possessing diesel-like properties[2].

1-Octanol

1-Octanol

🥰Excellent
Purity: 99.94%
Catalog No. T10024Alias OctanolCas No. 111-87-5
1-Octanol, a saturated fatty alcohol, functions as an inhibitor of T-type calcium channels (T-channels), showing an inhibitory concentration (IC50) of 4 μM for native T-currents[1]. Additionally, 1-Octanol is recognized for its potential as a biofuel, possessing diesel-like properties[2].
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 g$39-In Stock
10 g$56-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.94%
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Product Introduction

Bioactivity
Description
1-Octanol, a saturated fatty alcohol, functions as an inhibitor of T-type calcium channels (T-channels), showing an inhibitory concentration (IC50) of 4 μM for native T-currents[1]. Additionally, 1-Octanol is recognized for its potential as a biofuel, possessing diesel-like properties[2].
Targets&IC50
Ca2+ channel, T-type:4 μM
In vitro
1-octanol inhibits native T-currents at subanesthetic concentrations with an IC50 of approximately 4 μM, yet it is up to 30-fold less potent in inhibiting recombinant CaV3.3 T-channels heterologously expressed in human embryonic kidney cells [1].
SynonymsOctanol
Chemical Properties
Molecular Weight130.23
FormulaC8H18O
Cas No.111-87-5
SmilesCCCCCCCCO
Relative Density.0.827 g/cm3 at 25℃ (lit.)
ColorTransparent
AppearanceLiquid
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (383.94 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (15.36 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM7.6787 mL38.3936 mL76.7872 mL383.9361 mL
5 mM1.5357 mL7.6787 mL15.3574 mL76.7872 mL
10 mM0.7679 mL3.8394 mL7.6787 mL38.3936 mL
20 mM0.3839 mL1.9197 mL3.8394 mL19.1968 mL
50 mM0.1536 mL0.7679 mL1.5357 mL7.6787 mL
100 mM0.0768 mL0.3839 mL0.7679 mL3.8394 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

T-type calcium channelT-currentsT-channelssaturatedHuman Endogenous MetaboliteEndogenousMetaboliteEndogenous Metabolitediesel-likeCalciumChannelCalcium Channelbiofuelalcohol1-Octanol1Octanol1 Octanol
Related Tags: buy 1-Octanol | purchase 1-Octanol | 1-Octanol cost | order 1-Octanol | 1-Octanol chemical structure | 1-Octanol in vitro | 1-Octanol formula | 1-Octanol molecular weight
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