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Keliximab
(Synonyms: SB-210396, SB 210396, IDEC-CE9.1, IDEC CE9.1) Copy Product Info
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Synonyms: SB-210396, SB 210396, IDEC-CE9.1, IDEC CE9.1
Catalog No. T77049 Copy Product Info
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Keliximab (SB-210396), a chimeric human/macaque anti-CD4 monoclonal antibody, demonstrates binding affinity for soluble CD4 with a Ki value of 1.0 nM. Keliximab (SB-210396) inhibits T-cell proliferation and IL-2 production, making Keliximab (SB-210396) a valuable reagent for cancer research and immune signaling investigations. Keliximab (SB-210396) is additionally applicable to studies involving CD4-mediated immune activation and lymphocyte functional regulation.
Cas No. 174722-30-6
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $247 | - | In Stock | |
| 5 mg | $622 | - | In Stock | |
| 10 mg | $996 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.1% (SDS-PAGE); 97.8% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Keliximab (SB-210396), a chimeric human/macaque anti-CD4 monoclonal antibody, demonstrates binding affinity for soluble CD4 with a Ki value of 1.0 nM. Keliximab (SB-210396) inhibits T-cell proliferation and IL-2 production, making Keliximab (SB-210396) a valuable reagent for cancer research and immune signaling investigations. Keliximab (SB-210396) is additionally applicable to studies involving CD4-mediated immune activation and lymphocyte functional regulation. |
| In vivo | Keliximab (30mg/kg; i.p.) causes a 50% decrease in HuCD4+ cells that lasted for at least 12 days[1]. |
| Synonyms | SB-210396, SB 210396, IDEC-CE9.1, IDEC CE9.1 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | CD4 |
| Cas No. | 174722-30-6 |
| Isotype | Human IgG4 lambda |
| Recommended Isotype Control |
| Storage | Store at low temperature, -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Keliximab chemical structure | Keliximab in vivo
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